Evaluation by Standard Laboratory Tests of the Sixty-one Cases of Cancer Positive Reaction (Oncogene C-fos Ab2) in Liver（Among 1547 Cases）by the Bi-Digital O-Ring Test

Yasuhiro Shimotsuura M. D., F. I. C. A. E.

O-Ring Test Life Science Research Institute & Shimotsuura Clinic, Kurume, Fukuoka

 【Purpose】It is necessary five conditions of cancer diagnosis for the cancer screening method of Bi-Digital O-Ring Test（OMURA, Y. 1977-2000;BDORT）.  Among five conditions, cases  detected Oncogene C-fos Ab2 positive reaction ( the muscular power decline phenomenon) by BDORT, were evaluated by standard laboratory tests. Also the difference of BDORT medicine and modern medicine and merits, demerits were discussed.

【Subjects】1547 of outpatients (male;572, female;975) with various appeal were checked. They came from January 1999 to 31, May of 2000.

【Methods】Among the five conditions of cancer by BDORT (OMURA, Y. 1990-1992), patients with positive reaction of Oncogene C-fos Ab2 in liver parts were used BDORT imaging method of cancer or pre-cancer. Among them positive cases were checked by the blood biochemistry inspection, serology inspection, supersonic waves inspections, abdomen CT inspections, and MRI inspection etc. Method of the whole body screening by BDORT by using Oncogene C-fos Ab2 is as following: the third person holds the control reference substance of Oncogene C-fos Ab2（100ng）and scans from toe to head of the patient by using straight line state laser beam. And on the liver parts Oncogene C-fos Ab2 positive area was estimated and drawn the outline of abnormal reaction by using BDORT imaging method.

【Results】1. Among 1547 outpatients, 61 cases were Oncogene C-fos Ab2 positive in their liver and positive rate was 3.9%.

2. Among 61 cases cancer (Oncogene C-fos Ab2) positive by BDORT in their liver, cancer or pre-cancer positive cases were 9 (14.7%). Besides for the cancer cases were 6(9.83%).

3. Among all patients 9 cases were detected as cancer or pre-cancer. 9 cases were hepatocellular carcinoma,5;liver metastasis cancer, 1; malignant lymphoma, 1; adenomyositis of gallbladder, 1; gland tumor of lung,1.

4. Among 61 cases cancer (Oncogene C-fos Ab2) positive in their liver, 5 cases were diagnosed as hepatocellular carcinoma (8.2%) .

5. Among 61 cases cancer (Oncogene C-fos Ab2) positive in their liver, HCV positive cases were 39(64%) and HCV negative cases were 22(36%).

6. Five cases of hepatocellular carcinoma were all HCV positive and 0.32% among the outpatients. But among Oncogene C-fos Ab2 positive cases, HCV positive cases were 39 (12.8%).

7. Among 61 cases cancer (Oncogene C-fos Ab2) positive in their liver, 5 cases were diagnosed as hepatocellular carcinoma (8.2%) .

8. Among 61 cases cancer (Oncogene C-fos Ab2) positive in their liver, HCV positive cases were 39(64%) and HCV negative cases were 22(36%).

9. Five cases of hepatocellular carcinoma were all HCV positive and that rate was 0.32% of all of the outpatients.

10. Among Oncogene C-fos Ab2 positive patients by BDORT, HCV negative patients by blood test were 39 cases (2.5% among all patients) and the rate of hepatocellular carcinoma was 12.8% (5/39).

Case 1）M.S. 66 years old male　He was chronic hepatitis C type patient, and since 3 years ago Oncogene C-fos Ab2 positive reaction was appeared to the outside of the right part of liver. The results of BDORT were Oncogene C-fos Ab2；51ng、Integrina₅b₁；46ng、Hg；27ng、Acethylcholine；34mg、HCV；370ng, but no abnormality with the echo, CT, MRI inspection etc at different affiliation. In August, 1999 after three years past from his first examination hyperechoic mass of φ19 mm large was appeared to the liver right side (S6) marked by BDORT and diagnosed as hepatocellular carcinoma and an operation was done. Three years before diagnosed as hepatocellular carcinoma(HCC) by modern inspection method, this case was already commented the possibility of cancer reaction in the right leaf of his liver by BDORT. After 3 years passed, hepatocellular carcinoma was appeared as same place as indicated by BDORT. So it cannot be denied that HCC had already existed on the same place since 3 years ago.

Results）Among 1547 cases of outpatients checked by BDORT, the positive rate of Oncogene C-fos Ab2 was 3.9% and cancer or pre-cancer including hepatocellular carcinoma was detected in 9 cases(14.7%). In this study cases diagnosed as hepatocellular carcinoma were all HCV positive, so for the screening of the hepatocellular carcinoma the detection rate by cancer (Oncogene C-fos Ab2) positive reaction of BDORT was 8.2% of all positive patients. But in addition of the factor of HCV positive detection rate was increased to 12.8%. In consideration with these results, the factor of HCV positive should be added in the diagnosis of hepatocellular carcinoma. Besides there exists other factor such as AFP, PIVKA-2 etc. related to the hepatocellular carcinoma, so we need further research for the increasing detection rate of BDORT cancer screening of the hepatocellular carcinoma. Also, it was conceivable that there is significance for the prediction of cancer occurrence, from that HCC has appeared in the cancer reaction department of the liver and BDORT is important in preventive medicine.